West-Central Ghana Conference is a church administrative unit of the Seventh-day Adventist church in Ghana. The conference operates under Southern Ghana Union Conference of the West-Central Africa Division. It was organized in 2017 and consists of the following territories: central part of Western region of the Republic of Ghana; bounded on the north by Anyafuri, on the northeast by Twifo Nyinasi, on the west by Cote d’Ivoire, on the southeast by Mpohor district, and on the south by Ahanta West district. The conference headquarters is in Tarkwa, Ghana.